Guide To Leukemia Information
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Guide To Leukemia Information
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Guide To Leukemia Information
Cancer that starts in blood-forming tissue such as the bone marrow, and causes large numbers of blood cells to be produced and enter the bloodstream.

Adult acute lymphoblastic leukemia (ALL) is a type of cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell).


Adult acute lymphoblastic leukemia (ALL; also called acute lymphocytic leukemia) is a cancer of the blood and bone marrow. This type of cancer usually gets worse quickly if it is not treated.  Normally, the bone marrow produces stem cells (immature cells) that develop into mature blood cells. There are 3 types of mature blood cells:
Red Blood Cells that carry oxygen and other materials to all tissues of the body.
White Blood Cells that fight infection and disease.
Platelets that help prevent bleeding by causing blood clots to form.


In ALL (Leukemia) too many stem cells develop into a type of white blood cell called lymphocytes. These lymphocytes may also be called lymphoblasts or leukemic cells. There are 3 types of lymphocytes:
B lymphocytes that make antibodies to help fight infection.
T lymphocytes that help B lymphocytes make the antibodies that help fight infection.
Natural killer cells that attack cancer cells and viruses.


In ALL, the lymphocytes are not able to fight infection very well. Also, as the number of lymphocytes increases in the blood and bone marrow, there is less room for healthy white blood cells, red blood cells, and platelets. This may cause infection, anemia, and easy bleeding. The cancer can also spread to the central nervous system (brain and spinal cord).
Previous chemotherapy and exposure to radiation may affect the risk of developing ALL Leukemia.
Possible risk factors for ALL include the following:
Being male.
Being white.
Being older than 70.
Past treatment with chemotherapy or radiation therapy.
Exposure to atomic bomb radiation.
Having a certain genetic disorder such as Down Syndrome.
Possible signs of adult ALL include fever, feeling tired and easy bruising or bleeding.
The early signs of ALL may be similar to the flu or other common diseases. A doctor should be consulted if any of the following problems occur:
Weakness or feeling tired.
Fever.
Easy bruising or bleeding.
Petechiae (flat, pinpoint spots under the skin caused by bleeding).
Shortness of breath.
Weight loss or loss of appetite.
Pain in the bones or stomach.
Pain or feeling of fullness below the ribs.
Painless lumps in the neck, underarm, stomach, or groin.
These and other symptoms may be caused by adult acute lymphoblastic leukemia or by other conditions.
For more information visit the United States Government
National Institutes of Health Website